As experienced optometrists, we often receive questions about whether nutritional supplements can genuinely improve eye health or alleviate chronic symptoms. For many eye-related conditions, proper nutrition plays a supportive role. One area with substantial research backing is dry eye disease, where nutrition and targeted supplementation can deliver significant benefits.

Numerous clinical studies consistently show that a balanced diet combined with specific supplements can improve tear quality, reduce inflammation, and promote long-term comfort in the eyes. This compelling evidence highlights the necessity of integrating supplements into a holistic management plan for effectively addressing dry eye symptoms.
Two popular supplements in this context are Lacritec and DRYeye Forte. While both products aim to alleviate dry eye symptoms, they differ significantly in their formulations, strength, and how effectively their ingredients work within the body.
This comparative analysis clarifies these differences, enabling you to make an informed decision regarding your strategy for managing dry eye symptoms.
Thorough Ingredient Analysis for Lacritec and DRYeye Forte
Essential Ingredients Found in DRYeye Forte
- 667 mg re‑esterified omega‑3 triglycerides per capsule
- 240 mg EPA
- 160 mg DHA
- 455 mg borage oil supplying 100 mg GLA
- Vitamin D3 200 IU
- Natural vitamin E 40 IU
Core Ingredients in Lacritec
- 332 mg omega‑3 triglycerides per capsule
- 134 mg EPA
- 66.8 mg DHA
- 334 mg flaxseed oil
- Provides 192 mg ALA
- 434 mg borage oil supplying 95.5 mg GLA
- No vitamin D3
- No vitamin E


Exploring the Significance of Different Types of Omega‑3 Fatty Acids
Although both supplements contain omega‑3 fatty acids, it is crucial to understand that not all omega‑3s operate in the same manner within the body.
Lacritec includes flaxseed oil, which provides ALA. While ALA is recognized as an omega‑3 fatty acid, the human body only converts a small percentage of ALA into the more essential forms for alleviating dry eye symptoms, specifically EPA and DHA. Research suggests that the conversion rates of ALA to EPA are about 8–12 percent, with most ALA being utilized as an energy source rather than for eye health.
In contrast, DRYeye Forte provides EPA and DHA directly, utilizing higher concentrations in a re‑esterified format. This advanced method of manufacturing enhances both absorption and bioavailability, ensuring that a more significant proportion of the active ingredients effectively reaches the tissues where they are needed most.
When comparing the effective levels of EPA and DHA:
- Three capsules of DRYeye Forte deliver a substantially greater amount of EPA and DHA than three capsules of Lacritec.
- To match the EPA and DHA content found in three capsules of DRYeye Forte, you would need to take approximately six Lacritec capsules.
Both supplements recommend starting with three capsules daily during the treatment phase, making this difference clinically significant for users seeking effective relief.


Evaluating the Quality and Sourcing of Fish Oil
Both Lacritec and DRYeye Forte are manufactured in Australia and utilize high-quality fish oils derived from small, cold-water fish such as sardines and anchovies sourced from Peru. Smaller fish tend to accumulate fewer toxins, making them a safer option for supplementation. Both oils are subjected to rigorous purification and deodorization processes to remove impurities and reduce any unpleasant fishy aftertaste.
DRYeye Forte features re‑esterified triglyceride fish oil, which has proven superior absorption compared to traditional ethyl ester forms. This innovation not only enhances consistency but also minimizes gastrointestinal discomfort for many users, making it a preferred choice.
Understanding the Role of Vitamin D and Vitamin E in Promoting Eye Health
A key difference between the two supplements is that DRYeye Forte includes both vitamin D3 and natural vitamin E in its formulation, which can significantly influence eye health.
The Positive Effects of Vitamin D3 on Eye Health
Research indicates a strong correlation between low vitamin D levels and dry eye symptoms. Studies suggest that vitamin D may:
- Reduce ocular inflammation
- Improve tear stability
- Facilitate healing of the ocular surface
- Alleviate light sensitivity and overall ocular discomfort
The Multifaceted Benefits of Vitamin E
Vitamin E plays a vital dual role. It not only provides antioxidant and anti-inflammatory benefits but also safeguards omega‑3 fatty acids from oxidative damage. Long-term fish oil supplementation can elevate the body's need for vitamin E, making its inclusion essential for maintaining balance and optimizing omega‑3 metabolism.
In contrast, Lacritec does not include either vitamin D3 or vitamin E, which may restrict its overall effectiveness for supporting eye health.
Evaluating the Safety and Tolerability of Supplements
Both supplements are generally well tolerated when used according to the recommended dosage.
Possible side effects from either product may include mild gastrointestinal issues such as reflux, bloating, or loose stools. These effects are typically dose-dependent and can vary among individuals.
Individuals taking blood-thinning medications or who have bleeding disorders should consult a healthcare professional before starting either supplement.
Due to the presence of vitamin D3 in DRYeye Forte, those with hypercalcemia, kidney disease, or conditions sensitive to vitamin D should seek medical advice prior to use. In such cases, Lacritec may be a more appropriate choice due to its lack of vitamin D.
As with all supplements, it is advisable to consult a healthcare provider if you are pregnant, breastfeeding, or managing chronic health conditions.
Choosing the Best Supplement to Meet Your Needs
For most individuals suffering from moderate to severe dry eye disease, DRYeye Forte provides more comprehensive and targeted support. This is due to:
- Higher concentrations of effective EPA and DHA
- Improved absorption through the use of re‑esterified fish oil
- Inclusion of vitamin D3 and vitamin E, which help control inflammation and support tear production
Lacritec may still be appropriate for individuals with very mild symptoms or those who cannot tolerate vitamin D supplementation.

Essential Insights and Recommendations for Dry Eye Management
Both supplements can positively contribute to managing dry eye symptoms; however, they are not interchangeable.
DRYeye Forte offers higher therapeutic dosages of the most effective omega‑3 fatty acids, along with additional nutrients that help manage inflammation, improve tear quality, and support ocular surface health. For many patients, this results in more effective symptom relief with fewer capsules needed daily.
Ultimately, the best supplement is one that fits seamlessly into a personalized dry eye treatment plan. If you are unsure which product is best for your needs, we recommend consulting with your optometrist or healthcare provider for tailored guidance.
Lacritec vs DRYeye Forte Frequently Asked Questions
Which supplement provides better dry eye relief: Lacritec or DRYeye Forte?
For the majority of individuals who experience moderate to severe dry eye symptoms, DRYeye Forte stands out as the more effective choice. It contains higher levels of EPA and DHA, the active omega-3s known to reduce inflammation and enhance tear quality, along with vitamin D3 and vitamin E for additional support. Lacritec may still be beneficial in milder cases or when vitamin D supplementation is not advisable.
What are the key differences between Lacritec and DRYeye Forte?
The primary difference lies in their formulations and potency. DRYeye Forte features highly bioavailable re-esterified fish oils that deliver clinically significant doses of EPA and DHA, complemented by vitamin D3 and natural vitamin E. In contrast, Lacritec utilizes flaxseed oil, which provides ALA — an omega-3 source that is less efficient and has limited conversion into EPA and DHA.
How many Lacritec capsules are equivalent to the EPA/DHA dosage in DRYeye Forte?
To achieve the same levels of EPA and DHA found in three capsules of DRYeye Forte, you would need to consume approximately six Lacritec capsules. This is due to Lacritec's lower omega-3 concentration and its reliance on ALA, which only partially converts into the more bioactive forms that the body requires.
Is it safe to take DRYeye Forte if I have kidney disease or elevated calcium levels?
If you have kidney disease or hypercalcemia, it is important to consult your healthcare provider before starting DRYeye Forte. The inclusion of vitamin D3 may not be suitable for individuals with these conditions. In such cases, Lacritec, which does not contain vitamin D, may be a more appropriate alternative.
Will I need to take dry eye supplements indefinitely?
Not necessarily. Many individuals start treatment with a higher dosage (three capsules daily) for 6–8 weeks and then reassess their condition with their optometrist. Some may transition to a maintenance dosage or discontinue use altogether if their symptoms improve. However, ongoing supplementation may be beneficial for chronic or seasonal dry eye, especially if there are underlying issues like inflammation or oil gland dysfunction.
Lacritec vs DRYeye Forte: Which Supplement Is the Better Choice for Dry Eye Relief?
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